AA and DHA are decreased in paediatric AD/HD and inattention is ameliorated by increased plasma DHA
نویسندگان
چکیده
The purpose of this study was to assess long chain polyunsaturated fatty acid (LCPUFA) status in relation socio-behavioral outcomes children with Attention Deficit/Hyperactivity Disorder (AD/HD). In a case-control design, plasma phospholipid content assessed aged 5–12 years AD/HD and typically functioning children. Dietary intakes LCPUFAs arachidonic (AA; 20:4n6) docosahexaenoic (DHA; 22:6n3) were quantified using four-day food record, polymorphisms determined FADS1 FADS2, the Conners 3 Parent Rating Scales cross section AD/HD. Compared children, AA DHA 40% lower Median intake AA, but not DHA, higher compared Polymorphisms (rs174546) FADS2 (174575) associated linoleic (LA; 18:2n6) level. Plasma level inversely inattention score. Despite having an elevated diagnosed have reduction which may be due part desaturase (FADS) gene cluster or increased conversion AA-derived metabolites. Increasing ameliorate symptoms
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ژورنال
عنوان ژورنال: Human nutrition & metabolism
سال: 2023
ISSN: ['2666-1497']
DOI: https://doi.org/10.1016/j.hnm.2022.200183